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The code on the link given is still based on the old C - style API. In order to work fluently and much more readable, you could use the C++ interface easily for this.

// Original image
Mat inputImage = imread( 'location.jpg' );
// Use region of interest approach
Mat outputImage = inputImage( Rect(x, y, width, heigth) );

This can be easily placed into a loop for optimal going through the image.