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@jxb If you're planning to use Python, Then you can use powerful VidGear Python Library that automates the process of pipelining OpenCV frames into FFmpeg on any platform. Here's a basic python example:

# import libraries
from vidgear.gears import WriteGear
import cv2

output_params = {"-vcodec":"libx264", "-crf": 0, "-preset": "fast"} #define (Codec,CRF,preset) FFmpeg tweak parameters for writer

stream = cv2.VideoCapture(0) #Open live webcam video stream on first index(i.e. 0) device

writer = WriteGear(output_filename = 'Output.mp4', compression_mode = True, logging = True, **output_params) #Define writer with output filename 'Output.mp4' 

# infinite loop
while True:

    (grabbed, frame) = stream.read()
    # read frames

    # check if frame empty
    if not is grabbed:
        #if True break the infinite loop
        break


    # {do something with frame here}
        gray = cv2.cvtColor(frame, cv2.COLOR_BGR2GRAY)

    # write a modified frame to writer
        writer.write(gray) 

        # Show output window
    cv2.imshow("Output Frame", frame)

    key = cv2.waitKey(1) & 0xFF
    # check for 'q' key-press
    if key == ord("q"):
        #if 'q' key-pressed break out
        break

cv2.destroyAllWindows()
# close output window

stream.release()
# safely close video stream
writer.close()
# safely close writer

Source: https://github.com/abhiTronix/vidgear/wiki/Compression-Mode:-FFmpeg#2-writegear-classcompression-mode-with-opencv-directly

You can check out VidGear Docs for more advanced applications and features.

Hope that helps!