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calculate intensity for region of interest

hi. good time.I have a gray scale image with a bounding box in it.I want to calculate intensity for bounding box.the resolution of my picture is 720*750 and my rectangle is: rectangle(400,210,70,50).do you have any idea to calculate the intensity for this region of my image?Thanks a lot for you're help.

calculate intensity for region of interest

hi. good time.I have a gray scale image with a bounding box in it.I want to calculate intensity for bounding box.the resolution of my picture is 720*750 and my rectangle is: rectangle(400,210,70,50).do you have any idea to calculate the intensity for this region of my image?Thanks a lot for you're help.