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Hi,
I would fit a line through the big blob (or take the maxima points of the big blob, i.e. highest and lowest to specify a line) and check afterwards if e.g. the center of gravity of the small blobs is on the left or right side of the line.
see: https://math.stackexchange.com/questions/1435779/calculate-if-a-point-lies-above-or-below-or-right-to-left-of-a-line
or
https://stackoverflow.com/questions/1560492/how-to-tell-whether-a-point-is-to-the-right-or-left-side-of-a-line/1560510#1560510
